Silence Therapeutics plc (SLN)

Healthcare · NGM · US

$10.93+1.20% today

Price as at 1 Oct 2026, 08:25 UTC. Quotes are delayed.

Fundamentals

Market cap$671.26M
Return on equity-90.4%
52-week range$4.19 to $17.58

Valuation and ratings

Analyst target (mean)$33.00
Analyst range$10.00 to $75.00
Analysts with price targets6
Consensus viewbuy
Moat score37/100
Overall rating45/100, moderate quality

Silence Therapeutics plc trades at $10.93. We do not hold enough of the inputs to value this company with the confidence the estimate implies, so we publish no fair value for it rather than a number we would not defend.

Our moat model scores it 37 out of 100, which is little in the way of a moat. A moat is a structural reason competitors cannot take the profits away, and it matters more to a long holding period than any single quarter's numbers do.

SLN earnings and analyst estimates

Next earnings date5 Nov 2026 (in 34 days)
EPS estimate, next year-$0.38
Expected EPS growth-4.1%
Expected revenue growth+132.8%

Recommendation mix, 7 published ratings

6 buy0 hold1 sell

Estimates are the published analyst consensus and move often. An earnings date is scheduled, not certain, and a share tends to reprice most violently on the day itself.

About Silence Therapeutics plc

Silence Therapeutics plc, a biotechnology company, engages in the discovery and development of novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases. The company develops Divesiran (SLN124), which is in Phase 2 development for polycythemia vera, and SLN548 for complement-mediated renal diseases. It also develops Zerlasiran (SLN360) for cardiovascular disease associated with elevated lipoprotein(a); SLN312 for dyslipidemia; SLN365 for hypercholesterolemia; and SLN098 for obesity. The company was formerly known as SR Pharma plc and changed its name to Silence Therapeutics plc in May 2007. Silence Therapeutics plc was incorporated in 1994 and is headquartered in London, United Kingdom.

Industry: BiotechnologyEmployees: 88HQ: United Kingdom

Company profile, industry and headcount are as reported by our data provider and can lag a company's own filings by a reporting period. The annual report is the authority.

SLN passes 1 of our 30 screens today

Each screen prints the exact criteria it used, and the circumstances in which it is wrong.

Super investor ownership

5 of the funds we track reported a position in their latest SEC 13F filing. Largest first:

A word of warning on reading these figures: a 13F reports the market value of a holding, so a fund that traded nothing at all still appears to have sold when the price fell. We found 102 companies where the standard reading gives the opposite answer. Only the share count is honest.

SLN peers

The largest companies in the same industry (Biotechnology), then in the same sector.

Every healthcare company we cover is on the Healthcare hub.

Common questions

Which funds own SLN?

5 of the institutions we track reported a position in SLN in their most recent SEC 13F filing. A 13F is filed up to 45 days after quarter end, so it tells you what a fund held then, not what it holds now.

When does SLN report earnings next?

Silence Therapeutics plc is scheduled to report on 5 Nov 2026. Companies move earnings dates, so read it as scheduled rather than certain.

Where does SteadyShares get its SLN data?

Fundamentals for SLN come from company filings and exchange data, as listed on NGM; institutional ownership comes from SEC 13F filings. The share price shown was last refreshed on 1 Oct 2026, 08:25 UTC and is delayed. Our data quality score for this company is 75/100, which is the share of the inputs behind our scores that were actually available rather than assumed. Metrics we do not hold are left out of the page rather than estimated.

The full research page for SLN, with financial statements, ownership detail, peer comparison and alerts, is free inside the app.

Data from company filings, exchange quotes and SEC EDGAR 13F disclosures. Quotes are delayed. Metrics we do not have are left out rather than estimated. Educational information, not financial advice.