Xeris Biopharma Holdings, Inc. (XERS)

Healthcare · NMS

$9.56-4.21% today

Price as at 1 Oct 2026, 04:01 UTC. Quotes are delayed.

Fundamentals

Market cap$1.50B
P/E ratio124.1
Revenue growth (YoY)+38.3%
Profit margin3.8%
52-week range$5.25 to $11.33

Valuation and ratings

Fair value estimate$3.48
Upside to fair value-63.6%
Analyst target (mean)$11.29
Analyst range$8.00 to $18.00
Analysts with price targets7
Consensus viewstrong buy
Moat score41/100
Overall rating28/100, very low quality

Fair value: $3.48 (-63.6%), see how we got there

Xeris Biopharma Holdings, Inc. trades at $9.56, which is 64% above the $3.48 our fair value estimate puts on the business. On that measure it screens as expensive, which is not the same as saying it will fall.

Our moat model scores it 41 out of 100, which is little in the way of a moat. A moat is a structural reason competitors cannot take the profits away, and it matters more to a long holding period than any single quarter's numbers do.

It changes hands at 124.1 times earnings. Be careful reading that in isolation: for a cyclical business a low P/E arrives at the top of the cycle, when profits are peaking and about to fall, which is exactly when the shares look cheapest and are not.

XERS earnings and analyst estimates

EPS estimate, next year$0.39
Expected EPS growth+180.4%
Expected revenue growth+22.5%

Recommendation mix, 7 published ratings

6 buy1 hold0 sell

Estimates are the published analyst consensus and move often. An earnings date is scheduled, not certain, and a share tends to reprice most violently on the day itself.

About Xeris Biopharma Holdings, Inc.

Xeris Biopharma Holdings, Inc., a commercial-stage biopharmaceutical company, engages in developing and commercializing therapies for chronic endocrine and neurological diseases in Illinois. It offers Gvoke, a ready-to-use liquid-stable glucagon for the treatment of severe hypoglycemia in pediatric and adult patients; Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor for the treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome. It is also developing XP-8121, a once-weekly subcutaneous injection of levothyroxine that is in phase 3 clinical trial for the treatment of hypothyroidism. The company was incorporated in 2005 and is headquartered in Chicago, Illinois.

Industry: Drug Manufacturers - Specialty & GenericEmployees: 435HQ: United States

Company profile, industry and headcount are as reported by our data provider and can lag a company's own filings by a reporting period. The annual report is the authority.

XERS passes 2 of our 30 screens today

Each screen prints the exact criteria it used, and the circumstances in which it is wrong.

Super investor ownership

9 of the funds we track reported a position in their latest SEC 13F filing. Largest first:

A word of warning on reading these figures: a 13F reports the market value of a holding, so a fund that traded nothing at all still appears to have sold when the price fell. We found 102 companies where the standard reading gives the opposite answer. Only the share count is honest.

XERS peers

The largest companies in the same industry (Drug Manufacturers - Specialty & Generic), then in the same sector.

Every healthcare company we cover is on the Healthcare hub.

Common questions

Is Xeris Biopharma Holdings, Inc. (XERS) undervalued?

Against our fair value estimate of $3.48, XERS at $9.56 is 64% above fair value. That is one model's answer, not a recommendation. It is built from normalized earning power with growth capped deliberately low, which understates companies whose value is mostly future growth.

Which funds own XERS?

9 of the institutions we track reported a position in XERS in their most recent SEC 13F filing. A 13F is filed up to 45 days after quarter end, so it tells you what a fund held then, not what it holds now.

What is XERS's P/E ratio?

XERS trades at 124.1 times earnings. A low P/E is not automatically cheap: on a cyclical company it is usually a warning that earnings are at a peak.

Where does SteadyShares get its XERS data?

Fundamentals for XERS come from company filings and exchange data, as listed on NMS; institutional ownership comes from SEC 13F filings. The share price shown was last refreshed on 1 Oct 2026, 04:01 UTC and is delayed. Our data quality score for this company is 79/100, which is the share of the inputs behind our scores that were actually available rather than assumed. Metrics we do not hold are left out of the page rather than estimated.

The full research page for XERS, with financial statements, ownership detail, peer comparison and alerts, is free inside the app.

Data from company filings, exchange quotes and SEC EDGAR 13F disclosures. Quotes are delayed. Metrics we do not have are left out rather than estimated. Educational information, not financial advice.