Krystal Biotech, Inc. (KRYS)

Healthcare · NMS

$325.31-2.18% today

Price as at 1 Oct 2026, 23:23 UTC. Quotes are delayed.

Fundamentals

Market cap$10.01B
P/E ratio48.6
Revenue growth (YoY)+31.9%
Profit margin53.9%
Return on equity19.9%
52-week range$178.61 to $382.54

Valuation and ratings

Fair value estimate$269.11
Upside to fair value-17.3%
Analyst target (mean)$361.67
Analyst range$241.00 to $474.00
Analysts with price targets9
Consensus viewstrong buy
Moat score86/100
Overall rating55/100, good quality

Fair value: $269.11 (-17.3%), see how we got there

Krystal Biotech, Inc. trades at $325.31, which is 17% above the $269.11 our fair value estimate puts on the business. On that measure it screens as expensive, which is not the same as saying it will fall.

Our moat model scores it 86 out of 100, which is a wide moat. A moat is a structural reason competitors cannot take the profits away, and it matters more to a long holding period than any single quarter's numbers do.

It changes hands at 48.6 times earnings. Be careful reading that in isolation: for a cyclical business a low P/E arrives at the top of the cycle, when profits are peaking and about to fall, which is exactly when the shares look cheapest and are not.

KRYS earnings and analyst estimates

EPS estimate, next year$10.21
Expected EPS growth+21.3%
Expected revenue growth+29.7%

Recommendation mix, 11 published ratings

10 buy1 hold0 sell

Estimates are the published analyst consensus and move often. An earnings date is scheduled, not certain, and a share tends to reprice most violently on the day itself.

About Krystal Biotech, Inc.

Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States. The company commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). It also develops KB803 for ocular complications of dystrophic epidermolysis bullosa; KB801 for neurotrophic keratitis; KB407, which is in Phase 1 clinical trials for treating cystic fibrosis; KB111 for Hailey-Hailey disease; KB707 for solid tumors; KB304 for dynamic wrinkles; KB707 that is in Phase 1/2 clinical trials for the treatment of anti-PD-1 relapsed/refractory; KB408, which is in Phase 1 clinical trials for treating Alpha-1 antitrypsin deficiency; and KB301 that is in Phase 2 clinical trials for treating aesthetic skin conditions, as well as in open label study with ophthalmic B-VEC for treating for ocular complications of deb. Krystal Biotech, Inc. was founded in 2016 and is headquartered in Pittsburgh, Pennsylvania.

Industry: BiotechnologyEmployees: 295HQ: United States

Company profile, industry and headcount are as reported by our data provider and can lag a company's own filings by a reporting period. The annual report is the authority.

KRYS passes 5 of our 30 screens today

Each screen prints the exact criteria it used, and the circumstances in which it is wrong.

Super investor ownership

8 of the funds we track reported a position in their latest SEC 13F filing. Largest first:

A word of warning on reading these figures: a 13F reports the market value of a holding, so a fund that traded nothing at all still appears to have sold when the price fell. We found 102 companies where the standard reading gives the opposite answer. Only the share count is honest.

Politician trades in KRYS

Trades in KRYS disclosed by members of Congress and executive-branch officials, latest first:

  • Donald J Trump · Executive branchBuy · $1,001 - $15,000 · traded 15 Jun 2026 · disclosed 22 Aug 2026
  • Donald J Trump · Executive branchSell · $15,001 - $50,000 · traded 15 May 2026 · disclosed 1 Jul 2026
  • Donald J Trump · Executive branchSell · $100,001 - $250,000 · traded 24 Jul 2024 · disclosed 22 Sept 2026
  • Christopher L. Jacobs · HouseBuy · $1,001 - $15,000 · traded 12 Dec 2022 · disclosed 20 Jan 2023

A disclosure reports a value band, not an amount, and is due up to 45 days after the trade; some arrive later. Every filer we track, each with their own page, is on the Congress trading tracker.

KRYS peers

The largest companies in the same industry (Biotechnology), then in the same sector.

Every healthcare company we cover is on the Healthcare hub.

Common questions

Is Krystal Biotech, Inc. (KRYS) undervalued?

Against our fair value estimate of $269.11, KRYS at $325.31 is 17% above fair value. That is one model's answer, not a recommendation. It is built from normalized earning power with growth capped deliberately low, which understates companies whose value is mostly future growth.

Which funds own KRYS?

8 of the institutions we track reported a position in KRYS in their most recent SEC 13F filing. A 13F is filed up to 45 days after quarter end, so it tells you what a fund held then, not what it holds now.

What is KRYS's P/E ratio?

KRYS trades at 48.6 times earnings. A low P/E is not automatically cheap: on a cyclical company it is usually a warning that earnings are at a peak.

Where does SteadyShares get its KRYS data?

Fundamentals for KRYS come from company filings and exchange data, as listed on NMS; institutional ownership comes from SEC 13F filings. The share price shown was last refreshed on 1 Oct 2026, 23:23 UTC and is delayed. Our data quality score for this company is 96/100, which is the share of the inputs behind our scores that were actually available rather than assumed. Metrics we do not hold are left out of the page rather than estimated.

The full research page for KRYS, with financial statements, ownership detail, peer comparison and alerts, is free inside the app.

Data from company filings, exchange quotes and SEC EDGAR 13F disclosures. Quotes are delayed. Metrics we do not have are left out rather than estimated. Educational information, not financial advice.